The Amino-Terminal Region of Major Capsid Protein P3 Is Essential for Self-Assembly of Single-Shelled Core-Like Particles of Rice Dwarf Virus

Models, Molecular 0301 basic medicine 0303 health sciences Virus Assembly Virion Oryza Reoviridae Nucleopolyhedroviruses Cell Line 3. Good health Structure-Activity Relationship 03 medical and health sciences Animals Capsid Proteins Dimerization Gene Deletion
DOI: 10.1128/jvi.78.6.3145-3148.2004 Publication Date: 2004-02-27T21:47:38Z
ABSTRACT
The core protein P3 of Rice dwarf virus constructs asymmetric dimers, one which is inserted by the amino-terminal region another protein. proteins with serial deletions, expressed in a baculovirus system, formed particles gradually decreasing stability. capacity for self-assembly disappeared when 52 amino acids had been deleted. These results demonstrated that insertion arm into appears to play an important role stabilizing particles.
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