Uptake of the Siderophore Triacetylfusarinine C, but Not Fusarinine C, Is Crucial for Virulence of Aspergillus fumigatus

• DOI: 10.1128/mbio.02192-22
• Publication Date: 2022-09-20T13:04:36Z
• Authors: Mario Aguiar; Thomas Orasch; Yana Shadkchan; Patricia Caballero; Joachim Pfister; Luis Enrique Sast...; Fabio Gsaller; Clemens Decristoforo; Nir Osherov; Hubertus Haas
• Keywords: Virulence factor

Aspergillus fumigatus is responsible for thousands of cases invasive fungal disease annually. For iron uptake, A. secretes so-called siderophores, which are taken up after the binding environmental iron.