Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.

• DOI: 10.1128/mcb.1.9.854
• Publication Date: 2015-09-29T19:14:11Z
• Authors: S Subramani; R Mulligan; P Berg
• Keywords: Dihydrofolate reductase; Simian

A mouse complementary deoxyribonucleic acid segment coding for the enzyme dihydrofolate reductase has been cloned in two general classes of vectors containing simian virus 40 acid: (i) those that can be propagated as virions permissive cells and (ii) introduced into maintained stably various mammalian cells. Both types express by using signals supplied sequences. Moreover, plasmid carrying complement Chinese hamster ovary lacking reductase.