Tetrasodium EDTA Is Effective at Eradicating Biofilms Formed by Clinically Relevant Microorganisms from Patients’ Central Venous Catheters

0301 basic medicine Canada antibiotic resistance Bacteria EDTA Fungi Microbiology Gram-negative QR1-502 Hospitals 3. Good health Gram-positive 03 medical and health sciences Anti-Infective Agents Biofilms antimicrobial Central Venous Catheters Humans fungi Edetic Acid Research Article Calcium Chelating Agents
DOI: 10.1128/msphere.00525-18 Publication Date: 2018-11-27T11:37:48Z
ABSTRACT
The colonization of catheters by microorganisms often precludes their long-term use, which can be a problem for human patients that have few body sites available new catheters. colonizing organisms form biofilms, and increasingly these are resistant to multiple antibiotics, making them difficult treat. In this article, we taken associated with biofilm formation in from two Canadian hospitals tested tetrasodium EDTA, antimicrobial catheter lock solution. Tetrasodium EDTA was effective at eliminating Gram-positive, Gram-negative, fungal species represents promising alternative antibiotic treatment less chance the developing resistance. We expect our results will interest researchers clinicians lead improved patient care.
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