Clearance of Clostridioides difficile Colonization Is Associated with Antibiotic-Specific Bacterial Changes

• DOI: 10.1128/msphere.01238-20
• Publication Date: 2021-05-11T12:57:16Z
• Authors: Nicholas A. Lesniak; Alyxandria M. Sch...; Hamide Sinani; Patrick D. Schloss
• Keywords: Clostridioides; C difficile; Colonisation resistance

The community of microorganisms, or microbiota, in our intestines prevents pathogens like C. difficile from colonizing and causing infection. However, antibiotics can disturb the gut which allows to colonize. infections (CDI) are primarily treated with antibiotics, frequently leads recurrent because microbiota has not yet returned a resistant state.