A genome-scale metabolic model of a globally disseminated hyperinvasive M1 strain of Streptococcus pyogenes

• DOI: 10.1128/msystems.00736-24
• Publication Date: 2024-08-19T13:00:41Z
• Authors: Yujiro Hirose; Daniel C. Zielinski; Saugat Poudel; Kevin Rychel; Jonathon L. Baker; Yoshihiro Toya; Masaya Yamaguchi; Almut Heinken; Ines Thiele; Shigetada Kawabata; Bernhard O. Palsson; Victor Nizet
• Keywords: Streptococcus Pyogenes; Transposon mutagenesis; Auxotrophy; Flux Balance Analysis

is responsible for a range of diseases in humans contributing significantly to morbidity and mortality. Among more than 200 serotypes