Separation of Donor and Recipient Microbial Diversity Allows Determination of Taxonomic and Functional Features of Gut Microbiota Restructuring following Fecal Transplantation

• DOI: 10.1128/msystems.00811-21
• Publication Date: 2021-08-17T14:33:18Z
• Authors: Evgenii I. Olekhn...; Artem B. Ivanov; Vladimir I. Ulyan...; Elena N. Ilina
• Keywords: Colonisation resistance; Fecal bacteriotherapy

We assumed that the enrichment of successful gut microbes by lantibiotic/antibiotic resistance genes can be related to microbiota colonization third-party microbe phenomena and bacterium-derived or host-derived antimicrobial substances. According this assumption, competition between donor-derived recipient-derived as well host immunity may play a key role in FMT-related redistribution recipient structure.