The Cell–Cell Communication Signal Indole Controls the Physiology and Interspecies Communication of Acinetobacter baumannii

• DOI: 10.1128/spectrum.01027-22
• Publication Date: 2022-07-06T14:08:52Z
• Authors: Binbin Cui; Xiayu Chen; Quan Guo; Shihao Song; Mingfang Wang; Jingyun Liu; Yinyue Deng
• Keywords: Acinetobacter baumannii; 0301 basic medicine; Indoles; Quorum Sensing; Acyl-Butyrolactones; 3. Good health; 03 medical and health sciences; Bacterial Proteins; Escherichia coli; Type III Secretion Systems; Humans; Research Article

Acinetobacter baumannii is an important human opportunistic pathogen that usually causes high morbidity and mortality. It employs the N-acyl-L-homoserine lactone (AHL)-type quorum sensing (QS) system, AbaI/AbaR, to regulate biological functions and virulence.