Characterization of the Inflammatory Response Evoked by Bacterial Membrane Vesicles in Intestinal Cells Reveals an RIPK2-Dependent Activation by Enterotoxigenic Escherichia coli Vesicles

• DOI: 10.1128/spectrum.01115-23
• Publication Date: 2023-06-12T14:01:15Z
• Authors: Himadri B. Thapa; Paul Kohl; Franz G. Zingl; Dominik Fleischha...; Heimo Wolinski; Thomas A. Kufer; Stefan Schild
• Keywords: Gram-Negative Bacteria

The release of membrane vesicles from the bacterial cell surface is highly conserved among most species, including outer (OMVs) Gram-negative bacteria as well liberated cytoplasmic Gram-positive bacteria. It becoming increasingly evident that these multifactorial spheres, carrying membranous, periplasmic, and even cytosolic content, contribute to intra- interspecies communication.