Comparative Genomics of Listeria Species Recovered from Meat and Food Processing Facilities

• DOI: 10.1128/spectrum.01189-22
• Publication Date: 2022-09-06T13:01:13Z
• Authors: T. Mafuna; I. Matle; K. Magwedere; R. E. Pierneef; O. N. Reva
• Keywords: Comparative Genomics

Listeria species (spp.) are contaminants that can survive in food, on equipment, and food processing premises if appropriate hygiene measures not used. Homologous stress tolerance genes, virulence gene clusters such as the prfA cluster, of internalin genes contribute to pathogenic potential strains be carried by both nonpathogenic spp. To enhance understanding genome evolution virulence-associated properties, a comparative approach was used analyze 41 sequences belonging L. innocua welshimeri isolated from facilities. Genetic determinants responsible for disinfectant were identified, including efflux cassette bcrABC Tn6188_qac_1 resistance determinant, survival islets. These disinfectant-resistant more frequently found (12%) than (2%). Several isolates representing presumed still LGI2, LGI3, LIPI-3, LIPI-4 which absent all isolates. The mobile genetic elements identified plasmids (pLGUG1 J1776) prophages (PHAGE_Lister_vB_LmoS_188, PHAGE_Lister_LP_030_3, PHAGE_Lister_A118, PHAGE_Lister_B054, PHAGE_Lister_vB_LmoS_293). results suggest especially carry relevant strain's IMPORTANCE This study provides genomic insights into recently expanded genus order gain valuable information about properties distribution these pertinent across clonal lineages South Africa (SA).