EGCG Restricts PRRSV Proliferation by Disturbing Lipid Metabolism

• DOI: 10.1128/spectrum.02276-21
• Publication Date: 2022-04-11T13:02:06Z
• Authors: Peng-Wei Yu; Peng-Fei Fu; Lei Zeng; Yan-Li Qi; Xiu-Qing Li; Qi Wang; Guo-Yu Yang; Hua-Wei Li; Jiang Wang; Bei-Bei Chu; Meng-Di Wang
• Keywords: 0301 basic medicine; autophagy; Tea; Swine; Porcine Reproductive and Respiratory Syndrome; porcine reproductive and respiratory syndrome virus; Lipid Metabolism; Microbiology; Lipids; QR1-502; Catechin; Cell Line; 3. Good health; 03 medical and health sciences; lipid synthesis; Animals; epigallocatechin-3-gallate; Female; Porcine respiratory and reproductive syndrome virus; Research Article; Cell Proliferation

Porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped single-positive-stranded RNA virus that causes acute respiratory distress in piglets and reproductive failure in sows, resulting in huge economic losses to the global swine industry. Several lines of evidence have suggested the crucial roles of lipids in PRRSV proliferation.