Significance of Plasmodium berghei Amino Acid Transporter 1 in Food Vacuole Functionality and Its Association with Cerebral Pathogenesis

• DOI: 10.1128/spectrum.04943-22
• Publication Date: 2023-03-28T14:14:24Z
• Authors: Aditya Anand; Manjunatha Chandana; Sourav Ghosh; Rahul Das; Nalini Singh; Pradeep Mini Vais...; Nagavara Prasad G...; Govindarajan Padm...; Viswanathan Arun ...
• Keywords: 3. Good health; Research Article

Food vacuoles of the malaria parasite are involved in the degradation of red blood cell hemoglobin. The amino acids derived from hemoglobin degradation support parasite growth, and the heme released is detoxified into hemozoin.