Evaluation of the Novel CE-IVD-Marked Multiplex PCR QIAstat-Dx Meningitis/Encephalitis Panel

• DOI: 10.1128/spectrum.05144-22
• Publication Date: 2023-04-12T14:02:32Z
• Authors: Anu Humisto; Jenni Antikainen; Tanja Holma; Hanna Jarva; Anne Toivonen; Raisa Loginov; Laura Mannonen
• Keywords: 11832 Microbiology and virology; FilmArray; Bacteria; central nervous system infections; Csf; multiplex PCR; HSV-2; HSV-1; Microbiology; cerebrospinal fluid; QR1-502; 3. Good health; Cerebrospinal fluid; QIAstat; Viruses; Humans; Encephalitis; Meningitis; Hsv-1; Hsv-2; Multiplex Polymerase Chain Reaction; Central nervous system infections; Research Article

The diagnosis of infectious meningitis and encephalitis relies mostly on specific PCR and culturing methods, but commercial syndromic panel assays are bringing a change in diagnostics. With multiplexed analysis, the identification of the pathogen is potentially faster, and less sample material is needed.