Respiratory syncytial virus, human bocavirus and rhinovirus bronchiolitis in infants

• DOI: 10.1136/adc.2008.153361
• Publication Date: 2009-10-13T00:25:12Z
• Authors: F Midulla; C Scagnolari; E Bonci; A Pierangeli; G Antonelli; D De Angelis; R Berardi; C Moretti
• Keywords: Human bocavirus; Rhinovirus

To investigate the prevalence of 14 viruses in infants with bronchiolitis and to study demographic clinical differences those respiratory syncytial virus (RSV), human bocavirus (hBoV) rhinovirus (RV) infection.182 aged <12 months hospitalised for were enrolled. Infants underwent nasal washing detection RSV, influenza A B, coronavirus OC43, 229E, NL-63, HUK1, adenovirus, RV, parainfluenza 1-3, metapneumovirus hBoV. Demographic, laboratory data obtained from parents patient medical files. Main outcome measurements age, breastfeeding history, family smoking habits, history asthma atopy, blood eosinophil count, chest radiological findings, severity score number days hospitalisation.A was detected 57.2% 182 infants. The most frequently RSV (41.2%), hBoV (12.2%) RV (8.8%). dual infections (RSV hBoV) had a higher more hospitalisation than (mean+/-SD: 4.7+2.4 vs 4.3+/-2.4 3.0+/-2.0 2.9+/-1.7, p<0.05; 6.0+/-3.2 5.3+/-2.4 4.0+/-1.6 3.9+/-1.1 days; p<0.05). infection counts (307+/-436 138+/-168 89+/-19 n/mm(3); p<0.05).Although major pathogen responsible remains can also be caused by Demographic characteristics disease may depend on or specific detected.