Increased segmental activity and intraluminal pressures in the sigmoid colon of patients with the irritable bowel syndrome.

• DOI: 10.1136/gut.30.5.634
• Publication Date: 2007-09-18T21:41:31Z
• Authors: J Rogers; M M Henry; J J Misiewicz
• Keywords: Basal (medicine); Anus; Descending colon

Intraluminal pressure activity has been recorded in the unprepared true sigmoid colon of seven normal controls (mean age 37 years, range 22-55, three men) and patients with irritable bowel syndrome (IBS) (45 24-75, four for 30 minutes before 100 after a standard 1000 kcal meal. Results differ from previously published data by showing much higher indices amplitudes up to 490 mmHg IBS, 450 controls. Study segment index mean wave were significantly (p less than 0.015 p 0.01) IBS controls, but per cent duration was similar whole period study. During basal proximal (40 cm anus) those descending (50 cm), distal (30 cm) rectum (15 cm). This study shows that increased colonic is characterised amplitude, not waves. In state there high zone Pressures measured under other experimental conditions.