Endovascular interventions for acute stroke: past practice and current research

• DOI: 10.1136/neurintsurg-2015-011925
• Publication Date: 2015-07-29T01:11:50Z
• Authors: Jean Raymond; Jimmy Ghostine; Naim Khoury; Daniel Roy; Tim E Darsaut
• Keywords: Stroke

The way clinical care and research are currently conceived is entangled in multiple problems. While the problems universal, nowhere were they more painfully experienced than acute of patients with severe stroke. we celebrating that now possess evidence can benefit from endovascular interventions, should not miss opportunity to review difficult path led this point reflect on how it could be improved. A narrative past current status treatment stroke may serve expose potential solutions.

For 25 years, rescue interventions offered selected using a vast array drugs devices designed for purpose little success, at least early years.1 Occasionally, Lazarus experience (spectacular recovery associated recanalization) would fuel enough enthusiasm go another long run failures. We have always been aware occasional miracle justify full-scale campaign massive resources required staff centers expert personnel, streamlined patient transportation, mention generous budget needed such high-technology care. Clinical thus focused intravenous (IV) therapy, simpler approach which delivered locally.2 Following positive National Institute Neurological Disorders Stroke (NINDS) study, subsequent endeavors largely devoted neuroprotective agents promoted by pharmaceutical industry. Meanwhile, increasingly effective tools became available, but regulatory agencies never proof (angiographic demonstration vessels recanalized typically suffice) authorize sale ever expensive devices. Intra-arterial (IA) therapy did financial impetus rigorously assess outcomes. Until recently, presence large …