Frequency of sister chromatid exchange and chromosomal aberrations in asbestos cement workers.

• DOI: 10.1136/oem.48.2.103
• Publication Date: 2008-12-17T00:14:48Z
• Authors: N Fatma; A K Jain; Q Rahman
• Keywords: Sister chromatid exchange; Asbestos cement

Exposure to asbestos minerals has been associated with a wide variety of adverse health effects including lung cancer, pleural mesothelioma, and cancer other organs. It was shown previously that samples collected from local factory enhanced sister chromatid exchanges (SCEs) chromosomal aberrations in vitro using human lymphocytes. In the present study, 22 workers same 12 controls were further investigated. Controls matched for age, sex, socioeconomic state. The peripheral blood lymphocytes cultured harvested at 48 hours studies 72 SCE frequency determinations. Asbestos had raised mean rate increased numbers compared control population. Most gap break types.