Outdoor air pollution and respiratory health in patients with COPD

• DOI: 10.1136/thx.2010.155358
• Publication Date: 2011-04-02T02:45:06Z
• Authors: J. L. Peacock; H. R. Anderson; S. A. Bremner; L. Marston; T. A. Seemungal; D. P. Strachan; J. A. Wedzicha
• Keywords: Male; SYMPTOMS; Vital Capacity; 610; CHILDREN; Peak Expiratory Flow Rate; OBSTRUCTIVE PULMONARY-DISEASE; PANEL; Pulmonary Disease, Chronic Obstructive; 03 medical and health sciences; 0302 clinical medicine; SPUTUM; Air Pollution; Forced Expiratory Volume; 11. Sustainability; Humans; Aged; Air Pollutants; LONDON; MORTALITY; Urban Health; ADULTS; Middle Aged; 3. Good health; LUNG-FUNCTION; EXACERBATIONS; Dyspnea; 13. Climate action; Female; Environmental Monitoring; Follow-Up Studies

<h3>Objectives</h3> Time series studies have shown adverse effects of outdoor air pollution on mortality and hospital admissions in patients with chronic obstructive pulmonary disease (COPD) but panel been inconsistent. This study investigates short-term nitrogen dioxide, ozone, sulfur particulate matter (PM₁₀) black smoke exacerbations, respiratory symptoms lung function 94 COPD east London. <h3>Methods</h3> Patients were recruited from an outpatient clinic asked to complete daily diary cards (median follow-up 518 days) recording function, the amount time spent outdoors. Outdoor exposure (lag 1 day) was obtained local background monitoring stations. <h3>Results</h3> Symptoms not showed associations raised levels. Dyspnoea significantly associated PM₁₀ (increase odds for IQR change pollutant: 13% (95% CI 4% 23%)) this association remained after adjustment other pollutants measured. An increase dioxide a 6% (0–13%) symptomatic fall peak flow rate. The corresponding effect sizes 12% (2–25%) 7% (1–13%), respectively. <h3>Conclusion</h3> It is concluded that important living