Longitudinal Characterization of Cortical Lesion Development and Evolution in Multiple Sclerosis with 7.0-T MRI

• DOI: 10.1148/radiol.2019181719
• Publication Date: 2019-04-09T14:49:38Z
• Authors: Constantina A. Tr...; Tobias E. Granberg; Maria Pia Sormani; Elena Herranz; Russell A. Ouellette; Céline Louapre; Jacob A. Sloane; Revere P. Kinkel; Caterina Mainero
• Keywords: Adult; Cerebral Cortex; Male; Multiple Sclerosis; Middle Aged; 16. Peace & justice; Magnetic Resonance Imaging; White Matter; 03 medical and health sciences; Computer-Assisted; 0302 clinical medicine; Image Interpretation, Computer-Assisted; Disease Progression; Humans; Female; Prospective Studies; 10. No inequality; Image Interpretation

Background Cortical lesions develop early in multiple sclerosis (MS) and play a major role disease progression. MRI at 7.0 T shows high sensitivity for detection of cortical as well better spatial resolution signal-to-noise ratio compared with lower field strengths. Purpose To longitudinally characterize