Cerebral glioma: evaluation with methionine PET.

• DOI: 10.1148/radiology.186.1.8380108
• Publication Date: 2014-07-08T20:41:00Z
• Authors: T Ogawa; F Shishido; I Kanno; A Inugami; H Fujita; M Murakami; E Shimosegawa; H Ito; J Hatazawa; T Okudera
• Keywords: Adult; Male; Adolescent; Brain Neoplasms; Biopsy, Needle; Glioma; Astrocytoma; Middle Aged; 03 medical and health sciences; Methionine; 0302 clinical medicine; Humans; Female; Glioblastoma; Tomography, X-Ray Computed; Aged; Tomography, Emission-Computed

The authors examined 50 patients with cerebral glioma use of positron emission tomography (PET) and L-[methyl]-[11C]methionine to assess the grade malignancy extent glioma. Carbon-11 methionine was highly accumulated in lesion 31 32 high-grade 11 18 low-grade rate uptake C-11 significantly higher than (P < .001). However, individual cases it difficult evaluate only from degree accumulation. In most cases, area increased accumulation did not correspond abnormalities seen at computed (CT). Surgical intervention confirmed that PET delineated more clearly CT. concluded has greater utility assessing rather