Extraocular muscles in Graves ophthalmopathy: usefulness of T2 relaxation time measurements.

• DOI: 10.1148/radiology.190.3.8115640
• Publication Date: 2014-07-08T16:39:04Z
• Authors: T Ohnishi; S Noguchi; N Murakami; J Tajiri; M Harao; H Kawamoto; H Hoshi; S Jinnouchi; S Futami; S Nagamachi
• Keywords: Graves' ophthalmopathy; T2 relaxation

PURPOSE: To determine if T2 relaxation time measurements with magnetic resonance (MR) imaging in patients Graves ophthalmopathy (GO) can predict response to therapy. MATERIALS AND METHODS: Studied were 84 GO, 27 disease without (GD), and 12 control subjects disease. times of extraocular muscles retrobulbar fat tissue measured. Twenty-five GO treated systemic corticosteroids retroorbital radiation RESULTS: GD the same as those controls but longer (P < .05). all controls. The predicted probability treatment increased mean prior Of 25 combined therapy, only particularly prolonged showed impressive response. CONCLUSIONS: MR allow noninvasive detection acute muscle inflammation which will likely benefit from antiinflammatory