Effect of endurance training on glucose transport capacity and glucose transporter expression in rat skeletal muscle

• DOI: 10.1152/ajpendo.1990.259.6.e778
• Publication Date: 2017-12-22T05:52:59Z
• Authors: T. Ploug; B. M. Stallknecht; O. Pedersen; B. B. Kahn; T. Ohkuwa; J. Vinten; H. Galbo
• Keywords: Endurance Training

The effect of 10 wk endurance swim training on 3-O-methylglucose (3-MG) uptake (at 40 mM 3-MG) in skeletal muscle was studied the perfused rat hindquarter. Training resulted an increase approximately 33% for maximum insulin-stimulated 3-MG transport fast-twitch red fibers and contraction-stimulated slow-twitch compared with nonexercised sedentary muscle. A fully additive insulin contractions observed both trained untrained Compared control rats subjected to almost exhaustive single exercise session day before experiment insulin- rates were increased all types rats. Accordingly, glucose capacity not due a residual last session. Half-times reversal contraction-induced similar muscles. concentrations mRNA GLUT-1 (the erythrocyte-brain-Hep G2 transporter) GLUT-4 adipocyte-muscle twofold by fibers. In parallel this, Western blot demonstrated 47% protein 31% protein. This indicates that increases velocity is number transporters.