No sex differences in performance and perceived fatigability during a self-paced endurance exercise performed under moderate hypoxia

• DOI: 10.1152/ajpregu.00145.2024
• Publication Date: 2025-02-10T08:30:21Z
• Authors: Julio S. Hasegawa; Andre C. Silveira; Rafael A. Azevedo; Julio Cezar Schamne; Maria Urbana Pint...; Marcelo Papoti; Adriano Eduardo L...; Michael S. Koehle; Romulo Bertuzzi
• Keywords: Hypoxia; Cycling

This study examined potential sex differences on performance and perceived fatigability during a whole-body endurance exercise performed under normoxia or moderate hypoxia. Nine male eight female cyclists 4-km cycling time-trial hypoxia conditions. Performance its central peripheral determinants were measured via pre- to post-exercise changes in maximal voluntary isometric contraction (IMVC), activation (VA), potentiated twitch force (TwPt) of knee extensors, respectively. Perceived was characterized rating exertion (RPE). Time complete the trial longer than females (482 ± 24 vs 465 21 s) males (433 30 408 31 (P = 0.039). There no effect condition ≥ 0.370) for magnitude decrease IMVC (female: −14.3 4.4 %, −11.8 5.2 % male: −13.1 9.4 −12.9 9.8 %), TwPt −34.4 11.4 −31.8 18.9 −30.5 17.9 −31.9 20.9 VA −0.5 2.3 −1.6 1.6 0.8 2.2 1.3 %). RPE higher both groups 0.002). In conclusion, similarly impairs development time-trial.