Caffeine counteracts the ergogenic action of muscle creatine loading

• DOI: 10.1152/jappl.1996.80.2.452
• Publication Date: 2017-12-22T01:45:59Z
• Authors: K. Vandenberghe; N. Gillis; M. Van Leemputte; P. Van Hecke; F. Vanstapel; P. Hespel
• Keywords: Creatine; Exercise physiology; Gastrocnemius muscle

This study aimed to compare the effects of oral creatine (Cr) supplementation with in combination caffeine (Cr+C) on muscle phosphocreatine (PCr) level and performance healthy male volunteers (n = 9). Before after 6 days placebo, Cr (0.5 g x kg-1 day-1), or day-1) + C (5 mg supplementation, 31P-nuclear magnetic resonance spectroscopy gastrocnemius a maximal intermittent exercise fatigue test knee extensors an isokinetic dynamometer were performed. The consisted three consecutive isometric contractions interval series 90, 80, 50 voluntary performed rest 2 min between series. Muscle ATP concentration remained constant over experimental conditions. Cr+C increased (P < 0.05) PCr by 4-6%. Dynamic torque production, however, was 10-23% but not changed Cr+C. Torque improvement during most prominent immediately 2-min bouts. data show that elevates markedly improves intense exercise. ergogenic effect, is completely eliminated intake.