Training affects muscle phospholipid fatty acid composition in humans

• DOI: 10.1152/jappl.2001.90.2.670
• Publication Date: 2017-12-23T03:48:21Z
• Authors: Jørn W. Helge; Ben J. Wu; Mette Willer; Jens R. Daugaard; Leonard H. Storlien; Bente Kiens
• Keywords: Vastus lateralis muscle; Endurance Training

Training improves insulin sensitivity, which in turn may affect performance by modulation of fuel availability. Insulin action, turn, has been linked to specific patterns muscle structural lipids skeletal muscle. This study investigated whether regular exercise training exerts an effect on the membrane phospholipid fatty acid composition humans. Seven male subjects performed endurance knee extensors one leg for 4 wk. The other served as a control. Before, after days, and wk, biopsies were obtained from vastus lateralis. After contents oleic 18:1(n-9) docosahexaenoic 22:6(n-3) significantly higher trained (10.9 ± 0.5% 3.2 0.4% total acids, respectively) than untrained (8.8 2.6 0.4%, P < 0.05). ratio between n-6 n-3 acids was lower (11.1 0.9) (13.1 1.2, In contrast, did not triacylglycerol composition. Citrate synthase activity increased 17% compared with ( this model, diet plays minimal role, influence dietary intake is similar both legs. Regular per se influences membranes but no stored triacylglycerols within