Predicting tracheal work of breathing in neonates based on radiological and pulmonary measurements

• DOI: 10.1152/japplphysiol.00399.2022
• Publication Date: 2022-09-01T18:45:51Z
• Authors: Chamindu C. Gunat...; Erik B. Hysinger; Andreas Schuh; Qiwei Xiao; Deep B. Gandhi; Nara S. Higano; Daniel Ignatiuk; Md M. Hossain; Robert J. Fleck; Jason C. Woods; Alister J. Bates
• Keywords: Trachea; 03 medical and health sciences; 0302 clinical medicine; Infant, Newborn; Tidal Volume; Humans; Lung; Tracheomalacia; Work of Breathing; 3. Good health

The work of breathing due to resistance in the trachea is an important metric for quantifying the effect of tracheal abnormalities such as tracheomalacia, but currently requires complex dynamic imaging and computational fluid dynamics simulation to calculate it. This study produces a method to predict the tracheal work of breathing based on readily available imaging and clinical metrics.