Plasma corticosterone response to acute and chronic voluntary exercise in female house mice

• DOI: 10.1152/japplphysiol.00465.2001
• Publication Date: 2015-03-03T20:40:08Z
• Authors: I. Girard; T. Garland
• Keywords: Corticosterone; Wheel running; Turnover; Ratón

Plasma levels of corticosterone (B) respond acutely to exercise in all mammals that have been studied, but the literature contains conflicting reports regarding how chronic activity alters this response. We measured acute and effects voluntary on B a novel animal model, mice selectively bred for high wheel running. Female were housed with or without wheels 8 wk beginning at 26 days age. Wheel-access selection had significantly higher night 8, day 15, 29, compared wheel-access controls. Elevation was an effect exercise. When adjusted running previous 20 min, no difference between control animals remained. No training response observed. These results are among strongest evidence that, some animals, is unaffected by In wheels, than controls 50, suggesting resulted modulation hypothalamic-pituitary-adrenal axis. Growth over first 4 treatment inversely related average within each four groups.