Lower dynamic cerebral autoregulation following acute bout of low-volume high-intensity interval exercise in chronic stroke compared to healthy adults

• DOI: 10.1152/japplphysiol.00635.2023
• Publication Date: 2024-02-15T09:01:44Z
• Authors: Alicen A. Whitaker; Stacey E. Aaron; Mark Chertoff; Patrice Brassard; Jake Buchanan; Katherine Nguyen; Eric D. Vidoni; Saniya Waghmare; Sarah M. Eickmeyer; Robert N. Montgomery; Sandra A. Billinger
• Keywords: Adult; Middle Cerebral Artery; Blood Pressure; Middle Aged; Stroke; 03 medical and health sciences; 0302 clinical medicine; Cerebrovascular Circulation; Humans; Homeostasis; Arterial Pressure; Exercise; Blood Flow Velocity; Aged

This study provides novel insights into poststroke dynamic cerebral autoregulation (dCA) following an acute bout of high-intensity interval exercise (HIIE). In people after stroke, dCA appears attenuated during spontaneous fluctuations in mean arterial pressure (MAP) and middle cerebral artery blood velocity (MCAv) following HIIE. However, the dCA response during a single sit-to-stand transition after HIIE showed no significant difference from controls. These findings suggest that HIIE may temporarily challenge dCA after exercise in individuals with stroke.