Maturation of glutamatergic transmission onto dorsal raphe serotonergic neurons

• DOI: 10.1152/jn.00037.2023
• Publication Date: 2024-02-21T13:10:18Z
• Authors: Alexandre Kisner; Abigail M. Polter
• Keywords: 0301 basic medicine; 03 medical and health sciences; Article; Research Article

Serotonergic neurons are regulators of both the development of and ongoing activity in neuronal circuits controlling affective, cognitive, and sensory processing. Here, we characterize the maturation of extrinsic synaptic inputs onto these cells, showing that the first three postnatal weeks are a period of synaptic refinement and a potential window for experience-dependent plasticity in response to both enrichment and adversity.