Temporal dynamics of neocortical development in organotypic mouse brain cultures: a comprehensive analysis

• DOI: 10.1152/jn.00178.2024
• Publication Date: 2024-08-14T12:14:04Z
• Authors: Aniella Bak; Katharina Schmied; Morten L. Jakob; Francesco Bedogni; Olivia A. Squire; Birgit Gittel; Maik Jesinghausen; Kerstin D. Schüne...; Yvonne Weber; Björn Kampa; Karen M. J. van Loo; Henner Koch
• Keywords: Neocortex; Slice preparation

The development of the mouse neocortex in vitro mimics vivo development. Mouse brain cultures can serve as a model system for cortical first 2 wk and adult cortex from to 4 vitro. organotypic slice develop high-frequency network oscillations at γ frequency after exhibit increased heterogeneity variability culture.