Dynamic Circuitry for Updating Spatial Representations. III. From Neurons to Behavior

• DOI: 10.1152/jn.00330.2007
• Publication Date: 2007-05-10T00:59:04Z
• Authors: Rebecca A. Berman; Laura M. Heiser; Catherine A. Dunn; Richard C. Saunders; Carol L. Colby
• Keywords: Neurons; 0301 basic medicine; Behavior, Animal; Action Potentials; Motor Activity; Macaca mulatta; Functional Laterality; 03 medical and health sciences; 0302 clinical medicine; Nonlinear Dynamics; Memory; Space Perception; Reaction Time; Saccades; Animals; Visual Pathways; Nerve Net; Photic Stimulation; Visual Cortex

Each time the eyes move, visual system must adjust internal representations to account for accompanying shift in retinal image. In lateral intraparietal cortex (LIP), neurons update spatial of salient stimuli when move. previous experiments, we found that split-brain monkeys were impaired on double-step saccade sequences required updating across hemifields, as compared within hemifield. Here describe a subsequent experiment characterize relationship between behavioral performance and neural activity LIP monkey. We recorded from single while intact performed two conditions task: one across-hemifield other within-hemifield updating. that, despite extensive experience with task, significantly more accurate than sequences. parallel, population was stronger condition task. contrast, normal monkey, both average showed no bias toward condition. Finally, difference reflected at level single-neuron LIP. These findings indicate remapping area is present monkey task covaries behavior