An Olfacto-Hippocampal Network Is Dynamically Involved in Odor-Discrimination Learning

• DOI: 10.1152/jn.00524.2007
• Publication Date: 2007-08-15T20:33:44Z
• Authors: Claire Martin; Jennifer Beshel; Leslie M. Kay
• Keywords: Local field potential

Several studies have shown that memory consolidation relies partly on interactions between sensory and limbic areas. The functional loop formed by the olfactory system hippocampus represents an experimentally tractable model can provide insight into this question. It had been previously odor-learning associated beta band oscillations (15-30 Hz) of local field potential in rat are enhanced with criterion performance, but it was unknown if these involve networks beyond system. We recorded potentials from bulb (OB) dorsal ventral during acquisition odor discriminations a go/no-go task. These regions showed increased oscillation power sampling, accompanied coherence increase frequency OB both hippocampal subfields. This onset first rule transfer to new set remained high for all learning phases subsequent sets. However, two fields reset baseline levels each again performance. data support involvement network underlying odor-discrimination also suggest cooperation varies progress. Oscillatory activity range may thus mechanism which areas linked consolidation, similar proposed roles other systems long-range connections.