The uterine secretory cycle: recurring physiology of endometrial outputs that setup the uterine luminal microenvironment

• DOI: 10.1152/physiolgenomics.00035.2023
• Publication Date: 2023-09-11T08:31:51Z
• Authors: Kasey M. Schalich; Prasanthi P. Koganti; Juan M. Castillo; Olivia M. Reiff; Soon Hon Cheong; Vimal Selvaraj
• Keywords: Male; Mammals; Endometrium; Estrus; Pregnancy; Semen; Uterus; Animals; Female; Estrous Cycle

This study unravels the recurring sequence of changes within the uterus that supports vital functions (sperm transit and development of preimplantation embryonic stages) during the reproductive cycle in female Ruminantia. These data present new systems knowledge in uterine reproductive physiology crucial for setting up in vitro biomimicry and artificial environments for assisted reproduction technologies for a range of mammalian species.