Temporal Bacteriostatic Effect and Growth Factor Loss in Equine Platelet Components and Plasma Cultured with Methicillin-Sensitive and Methicillin-ResistantStaphylococcus aureus: A ComparativeIn VitroStudy

• DOI: 10.1155/2014/525826
• Publication Date: 2014-11-24T16:01:04Z
• Authors: Catalina López; María E. Álvarez; Jorge U. Carmona
• Keywords: Bacterial growth

The aims were (1) to evaluate the bacteriostatic effect of platelet-rich plasma (PRP), gel (PRG), leukocyte-poor (LPP), (LPG), plasma, and heat-inactivated (IP) on both methicillin-sensitive Staphylococcus aureus (MSSA) methicillin-resistant (MRSA) over a period 24 h; (2) determine compare concentrations degradation time platelet factor 4 (PF-4), transforming growth beta 1 (TGF- β ), platelet-derived isoform BB (PDGF-BB); (3) identify any correlations between MSSA MRSA either cellular, PF-4, TGF- , or PDGF-BB in blood components. PRP its byproducts from 18 horses obtained by tube method. All components cultured with MRSA. Bacterial growth, determined at 6 h h. At six hours, bacterial was significantly inhibited all components, exception IP. more sensitive treatments than higher PRP, LPP, when compared MSSA. Growth not affected bacteria.