Properties of Skin in Chinese Infants: Developmental Changes in Ceramides and in Protein Secondary Structure of the Stratum Corneum

• DOI: 10.1155/2017/3594629
• Publication Date: 2017-10-02T17:00:57Z
• Authors: Chao Yuan; Ying Zou; Yao Xueqiu; Kyoko Shima; Yuki Miyauchi; Ayano Naoe; Satoru Naito; Tsutomu Fujimura; Mitsuyuki Hotta; Takashi Kitahara; Xuemin Wang
• Keywords: Transepidermal water loss; Buttocks; Skin Barrier

The properties of infant skin regarding its structure and stratum corneum (SC) during development compared to adult have been reported only for a few races body sites. aim this study was understand the developmental changes in Chinese infants, focusing on SC ceramides protein secondary structure, which are important barrier function. Three sites with distinct characteristics (cheeks, inner upper arms, buttocks) were assessed. Sixty pairs infants their mothers measured hydration, transepidermal water loss, ceramide levels, sebum an ester bond, superficial SC. Skin hydration decreased age at all TEWL similar between 2–12- 13–24-month-old groups but higher than group buttocks arms equal cheeks. These differences coincided structure. Ceramide levels lower groups. We conclude that both functions components still developing not fully adapted as each site examined.