HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

• DOI: 10.1158/1078-0432.ccr-16-2191
• Publication Date: 2017-05-10T00:50:25Z
• Authors: Xiaowei Xu; Carmine De Angelis; Kathleen A. Burke; Agostina Nardone; Huizhong Hu; Lanfang Qin; Jamunarani Veerar...; Vidyalakshmi Seth...; Laura M. Heiser; Nicholas Wang; Charlotte K.Y. Ng; Edward S. Chen; Alexander Renwick; Tao Wang; Sarmistha Nanda; Martin Shea; Tamika Mitchell; Mahitha Rajendran; Ian Waters; Daniel J. Zabransky; Kenneth L. Scott; Carolina Gutierrez; Chandandeep Nagi; Felipe C. Geyer; Gary C. Chamness; Ben H. Park; Chad A. Shaw; Susan G. Hilsenbeck; Mothaffar F. Rimawi; Joe W. Gray; Britta Weigelt; Jorge S. Reis-Filho; C. Kent Osborne; Rachel Schiff
• Keywords: Acquired resistance; Targeted Therapy

Resistance to anti-HER2 therapies in HER2