Sarcoma Formation in an Autologous Graft of Mammary Tissue

• DOI: 10.1158/ajc.1938.549
• Publication Date: 2013-06-06T18:37:48Z
• Authors: A. Fischer
• Keywords: Mammary tissue

The occurrence of mammary carcinoma in mice and an epidermoid cyst, following repeated autologous transplantation tissue has been reported earlier papers (1). present report concerns a round-cell sarcoma which appeared the same procedure. It is uncertain whether this tumor arose from stroma or interstitial cells transplanted whether, indeed, it may not be coincidence having nothing to do with graft. Exp. No. 1666–3: On Oct. 26, 1936, right inguinal gland mouse was removed, sutured piece tail as experiments, grafted intramuscularly on back neck. Nov. 21 graft had increased size; found contain rather large parenchymatous tumor, re-implanted subcutaneously left flank. Dec. 12 animal died. At autopsy at site flank, part solidly adherent overlying skin, underlying muscles. liver lungs contained small, gray tumor-like lesions. spleen much enlarged.