Cerebral Anomalies and Chiari Type 1 Malformation

• DOI: 10.1159/000327220
• Publication Date: 2011-05-03T08:15:15Z
• Authors: Marcelo Galarza; Juan F. Martínez-...; Steven Ham; Sandeep Sood
• Keywords: Ventriculomegaly; Chiari Malformation

<i>Objective:</i> To analyze the association of diverse cerebral anomalies in a series pediatric patients with cerebellar tonsillar ectopia. <i>Methods:</i> We reviewed medical records 60 children diagnosed Chiari type 1 malformation (CM1), these, 20 (11 boys and 9 girls; mean age 7.2 years, range 2–16 years) had an associated anomaly. Symptoms ectopia evolved over 12 months (range 3 to 4 years). Syringomyelia was present 5 cases. All underwent posterior fossa decompression. <i>Results:</i> Disclosed included: congenital hydrocephalus (n = 11), cervicomedullary kinking 5), focal heterotopia epilepsy 4), partial agenesis corpus callosum hypoplastic brain stem 2), holoprosencephaly 1), subcortical dysplasia context neurofibromatosis 1). Other malformations hamartoma 1, craniofacial dysmorphism secondary Noonan syndrome, occipital plagiocephaly, os odontoideum, cleft, juvenile rheumathoid arthritis platybasia, osteogenesis imperfecta bathrocephaly scoliosis. <i>Conclusion:</i> Craniocerebral treated for CM1 may be found consistently. The hydrocephalus, which most common anomaly this cohort, contribute poor outcome regard herniation symptoms.