Carotid Artery Stenosis as a Cause of Stroke

• DOI: 10.1159/000341410
• Publication Date: 2012-10-19T15:39:52Z
• Authors: Matthew L. Flaherty; Brett Kissela; Jane C. Khoury; Kathleen Alwell; Charles J. Moomaw; Daniel Woo; Pooja Khatri; Simona Ferioli; Opeolu Adeoye; Joseph P. Broderick; Dawn Kleindorfer
• Keywords: Stroke

<b><i>Background:</i></b> Population-based studies have estimated that about 15% of ischemic strokes are caused by large-vessel cerebrovascular disease. We determined the types atherosclerosis responsible for in a population-based stroke study. <b><i>Methods:</i></b> Patients with first-ever or recurrent Greater Cincinnati area were identified during 2005 at all local hospitals. Study physicians assigned subtypes. Overall event rates and incidence events calculated, age-, race- sex-adjusted to 2000 US population. <b><i>Results:</i></b> There 2,204 strokes, including 365 subtype (16.6% strokes). Extracranial internal carotid artery (ICA) stenosis was associated 8.0% while extracranial ICA occlusion intracranial each 3.5% strokes. The annual rate attributed 13.4 (11.4–15.4) per 100,000 persons. conservatively estimate 41,000 may be annually United States. <b><i>Conclusions:</i></b> Large-vessel is an important cause stroke, being significantly more common than atherosclerotic