Risk Factor, Age and Sex Differences in Chronic Kidney Disease Prevalence in a Diabetic Cohort: The Pathways Study

• DOI: 10.1159/000342210
• Publication Date: 2012-09-17T07:08:29Z
• Authors: Margaret K. Yu; Courtney Rees Lyles; Luis A. Bent-Shaw; Bessie A. Young
• Keywords: Blood Glucose; Male; 2. Zero hunger; Age Factors; Middle Aged; 3. Good health; Cohort Studies; Diabetes Complications; 03 medical and health sciences; Cross-Sectional Studies; Sex Factors; 0302 clinical medicine; Risk Factors; Hypertension; Diabetes Mellitus; Prevalence; Humans; Kidney Failure, Chronic; Female; 10. No inequality; Aged; Glomerular Filtration Rate

<b><i>Background/Aims:</i></b> Women with diabetes experience a disproportionately greater burden of diabetic kidney disease (DKD) risk factors compared to men; however, sex-specific differences in DKD are not well defined. The effect age on sex is unknown. <b><i>Methods:</i></b> We performed cross-sectional analysis the prevalence (eGFR <60 ml/min/1.73 m<sup>2</sup> or microalbuminuria), advanced <30 m<sup>2</sup>), and common Pathways Study (n = 4,839), prospective cohort study patients from managed care setting. Subjects were stratified by ≥60 years examine for age. Logistic regression models examined association between factors. <b><i>Results:</i></b> all ages had 28% decreased odds (OR 0.72, 95% CI 0.62–0.83); they 1.67, 1.05–2.64), dyslipidemia 1.42, 1.16–1.74), obesity 1.87, 1.60–2.20) men. similar hypertension poor glycemic control as increased DKD, hypertension, dyslipidemia, similarly aged their male counterparts. <b><i>Conclusion:</i></b> an men these disparities most prominent amongst elderly.