Immunological Implications of Physical Inactivity among Older Adults during the COVID-19 Pandemic

• DOI: 10.1159/000509216
• Publication Date: 2020-06-25T21:00:30Z
• Authors: Anthony Damiot; Ana Jéssica Pinto; James E. Turner; Bruno Gualano
• Keywords: Social Isolation; Pandemic; Social distance; Isolation; Immunosenescence

Social distancing has been adopted worldwide to control severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. isolation is likely lead a decline in physical activity, which could result immune system dysfunction, thereby increasing infection susceptibility and exacerbating the pathophysiology of conditions that are common among older adults, including cardiovascular disease, cancer, inflammatory disorders. Older adults people living with these comorbidities at greater risk for complications during disease 2019 (COVID-19). In this review, we discuss negative impact inactivity on function showcase evidence regular activity may be an effective strategy counter some deleterious effects social isolation. Furthermore, briefly highlight key research questions exercise immunology, focus context COVID-19. Although it worth emphasizing there no direct can prevent or treat ­COVID-19, promoting active lifestyle intervention counteract isolation, especially other at-risk individuals, such as those chronic diseases associated ageing lifestyle.