Socio-Environmental, Lifestyle, Behavioural, and Psychological Determinants of Biological Ageing: The Singapore Longitudinal Ageing Study

• DOI: 10.1159/000511211
• Publication Date: 2020-11-16T22:00:33Z
• Authors: Tze Pin Ng; Xin Zhong; Qi Gao; Xinyi Gwee; Denise Qian Ling ...; Anis Larbi
• Keywords: Spouse

<b><i>Introduction:</i></b> The identification of modifiable health span-promoting factors is a public priority. <b><i>Objective:</i></b> To explore the socio-environmental, lifestyle, behavioural, and psychological determinants clinical phenotypic measure biological ageing in Singapore Longitudinal Ageing Study (SLAS) cohort. <b><i>Methods:</i></b> Using cross-sectional data on 2,844 SLAS-2 adults with chronological age (CA) ≥55 years, we estimated (BA) using validated panel clinical, biochemical, physiological, functional indicators (8 men 10 women) calculated difference between BA CA (BA – years). Potential included education, housing status, loss spouse, living alone, lifestyle activity, smoking, alcohol consumption, nutritional risks, consumption milk, soy, fruit, vegetables, coffee tea, sleep parameters, life satisfaction. <b><i>Results:</i></b> mean was 67.0 (standard deviation [SD] 7.9; range 55–94) years. varied more widely (SD 8.9 years; 47.5–119.9 years), ranged from –11.3 to 30.0 In stepwise selection regression analyses, multiple significant independent final model were larger for private housing, being single/divorced/widowed, productivity, cognitive leisure time activity scores, h/week moderate-to-vigorous physical unintended weight, satisfaction, daily fruits 1–2 or ≥3 servings Chinese tea cups daily, together explaining 16% variance 14% women. Associated estimates highest high-end status (–1.8 effect size 0.015) weight (1.5 0.017). <b><i>Conclusion:</i></b> We identified which can promote span.