A nation-wide analysis of venous thromboembolism in 497,180 cancer patients with the development and validation of a risk-stratification scoring system

• DOI: 10.1160/th12-01-0010
• Publication Date: 2012-04-26T07:46:09Z
• Authors: Chun-Yu Liu; Muh-Hwa Yang; Shu-Chiung Chiang; Hui-Chi Hsu; Ying-Chung Hong; Liang-Tsai Hsiao; Jin-Hwang Liu; Tzeon-Jye Chiou; Po-Min Chen; Tzong-Shyuan Lee; Li-Fang Chou; Cheng-Hwai Tzeng; Yuan-Bin Yu; Jyh-Pyng Gau; Tzeng-Ji Chen
• Keywords: Risk Stratification; Stratification (seeds)

Summary The Asian population is thought to have a low risk of venous thromboembolism (VTE), but the epidemiology VTE in cancer patients remains unclear. National Health Insurance Research Database Taiwan was used find hospitalised newly-diagnosed with determine incidence and identify factors for VTE. Between 1997 2005, 497,180 were identified. During median follow-up 21.3 months (range 0–119.9 months), 5,296 developed estimated 185 events per 100,000 person-years. Patients prior history female between ages 40 80 carried high rate relatively myeloma, prostate cancer, lung gynaecologic cancers, sarcoma, metastasis unknown origin. We risk-stratification scoring system divide into four discrete groups (very risk, intermediate, risk). each group 0.5%, 0.9%, 1.5%, 8.7%, respectively (p < 0.001). This validated separate patient cohort. In conclusion, distinct burden Taiwan. could prove helpful decision-making concerning thromboprophylaxis patients. Note: results this paper presented as an Asian-Pacific Scholarship Award at 23rd Congress International Society on Thrombosis Haemostasis, Kyoto, Japan, 23–28 July 2011.