Diastolic Blood Pressure Changes During Exercise Positively Correlate With Serum Cholesterol and Insulin Resistance

• DOI: 10.1161/01.cir.101.6.611
• Publication Date: 2012-06-12T00:42:29Z
• Authors: Sally E. Brett; James M. Ritter; Philip J. Chowien...
• Keywords: Adult; Male; 2. Zero hunger; Adolescent; 610; Blood Pressure; Middle Aged; 03 medical and health sciences; Cholesterol; 0302 clinical medicine; Diabetes Mellitus, Type 2; 616; Humans; Insulin Resistance; Exercise; Aged

Metabolic factors, including plasma concentrations of cholesterol and insulin resistance, may influence blood pressure through effects on vascular reactivity. Such might during exercise more strongly than at rest.We examined whether there is an association between serum or resistance change in mild exercise. Blood was measured rest fixed low-workload bicycle ergometry (50, 75, 100 W, each for 3 minutes) 75 healthy active men (age, 18 to 66 years). not significantly correlated with (estimated from the fasting glucose-insulin product). The resting values diastolic but systolic (R>0.47, P<0.0001 workload) (R>0.38, P<0.01 workload). Serum were only independent predictors a stepwise regression model incorporating age, body mass index, cholesterol, triglycerides, HDL heart rate In further study, greater uncomplicated type 2 diabetes (13.6 mm Hg [95% CI, 8.5 18.8]; n=10) nondiabetic control (2.7 -2. 0 7.3]; n=10; P=0.002).Changes gentle are associated total resistance. This contribute development hypertensive complications dyslipidemic and/or insulin-resistant patients.