Nonischemic ventricular tachycardia. Clinical course and long-term follow-up in patients without clinically overt heart disease.

• DOI: 10.1161/01.cir.79.5.990
• Publication Date: 2011-06-17T20:29:13Z
• Authors: R Lemery; P Brugada; P D Bella; T Dugernier; A van den Dool; H J Wellens
• Keywords: Adult; Male; Pacemaker, Artificial; Time Factors; Heart Diseases; Cardiac Pacing, Artificial; 12. Responsible consumption; 3. Good health; Electrophysiology; Electrocardiography; 03 medical and health sciences; 0302 clinical medicine; Echocardiography; Heart Conduction System; Tachycardia; Exercise Test; Humans; Female; Anti-Arrhythmia Agents; Follow-Up Studies

This report describes the clinical, laboratory, and electrophysiologic features of 52 patients with ventricular tachycardia (VT) who had no clinical evidence heart disease. The mean age was 36 years, cardiovascular collapse occurred in 18 (35%), exercise-related symptoms were present 24 49 (49%). There 20 sustained monomorphic VT, 11 incessant 21 nonsustained VT. Abnormalities 14 38 (37%) during echocardiography 47 (45%) underwent cardiac catheterization. During baseline evaluation while not receiving antiarrhythmic drugs, ambulatory monitoring exercise testing showed an 88% 57% incidence, respectively, or whereas 31 50 (62%) inducible VT (requiring infusion isoproterenol patients) programmed electrical stimulation. (when a 12-lead electrocardiogram available for analysis) left bundle branch block (LBBB) configuration 33 (61%) right axis deviation 17 (51%). occurring stimulation same as 22 patients. Three have received antitachycardia pacemaker, one patient endocardial resection. Forty-eight (92%) treated medically. One died cancer; remaining alive at follow-up 96 months after initial 46 We conclude that without disease, may be incessant, sustained, originates from outflow tract more than 50% Although abnormalities found 30% patients, exact significance these is unclear because absence progressive changes excellent prognosis this group