Ambulatory Blood Pressure and 10-Year Risk of Cardiovascular and Noncardiovascular Mortality

• DOI: 10.1161/01.hyp.0000152079.04553.2c
• Publication Date: 2005-01-27T21:27:54Z
• Authors: Masahiro Kikuya; Takayoshi Ohkubo; Kei Asayama; Hirohito Metoki; Taku Obara; Shin Saito; Junichiro Hashimoto; Kazuhito Totsune; Haruhisa Hoshi; Hiroshi Satoh; Yutaka Imai
• Keywords: Censoring (clinical trials); Prehypertension

The objective of this study was to elucidate the long-term prognostic significance ambulatory blood pressure. Ambulatory and casual pressure values were obtained from 1332 subjects (872 women 460 men) aged >or=40 years general population a rural Japanese community. Survival then followed for 14 370 patient analyzed by Cox hazard model adjusted possible confounding factors. There 72 cardiovascular deaths during 10.8-year follow-up. relationship between 24-hour systolic mortality risk U-shaped in first 5 years, changed J-shaped over rest After censoring 2 data, flattened until it again increased fifth quintile follow-up period. For diastolic pressure, remained unchanged, regardless duration censoring. consistently showed stronger predictive power than did whereas such relationships became more marked after years. When nighttime daytime simultaneously included same model, only significantly predicted data. We conclude that is not or J-shaped, has better value