A Longitudinal Study of Hypertension Risk Factors and Their Relation to Cardiovascular Disease

• DOI: 10.1161/01.hyp.0000200710.29498.80
• Publication Date: 2006-01-24T01:44:00Z
• Authors: Wenyu Wang; Elisa T. Lee; Richard R. Fabsitz; Richard Devereux; Lyle Best; Thomas K. Welty; Barbara V. Howard
• Keywords: Male; Aging; Alcohol Drinking; Cohort Studies; Diabetes Complications; 03 medical and health sciences; 0302 clinical medicine; Risk Factors; Albuminuria; Humans; Longitudinal Studies; Obesity; 10. No inequality; Aged; 2. Zero hunger; Smoking; Middle Aged; Overweight; 16. Peace & justice; 3. Good health; Cardiovascular Diseases; Hypertension; Indians, North American; Female

This study estimated hypertension incidence and explored risk factors their association with cardiovascular disease. Data collected from 4549 American Indian participants in the 3 exams of Strong Heart Study were used. Hypertension was defined as systolic blood pressure ≥140 mm Hg, diastolic ≥90 or current use antihypertensive medication. Generalized linear models used to identify for correlates pressures. Cox proportional time-dependent covariates mixed explore There no sex difference hypertension. After adjustment other factors, risks developing among subgroups each characterized group follows: prehypertensive versus normotensive, 3.21 times; macroalbuminuria microalbuminuria normal, 3.47 1.72; diabetic nondiabetic, 1.56; overweight obese normal weight, 1.30 1.51; alcohol drinking not, 1.22. Moreover, significantly positively associated age, obesity, albuminuria negatively smoking. adjusting all those pretreated, untreated, controlled, uncontrolled hypertensive had &1.74, 1.81, 2.19, 2.77 times higher disease compared normotensive participants, respectively. In 45- 74-year-old Indians, rising. Prehypertensive 3.2/1.74 hypertension/cardiovascular than participants. Age, diabetes, macro/microalbuminuria independently significant both