Reference Values for 24-Hour Ambulatory Blood Pressure Monitoring Based on a Prognostic Criterion

• DOI: 10.1161/01.hyp.32.2.255
• Publication Date: 2012-06-12T00:53:46Z
• Authors: Takayoshi Ohkubo; Yutaka Imai; Ichiro Tsuji; Kenichi Nagai; Sadayoshi Ito; Hiroshi Satoh; Shigeru Hisamichi
• Keywords: Reference values

Abstract —Although reference values for ambulatory blood pressure (ABP) monitoring have been investigated in several population studies, these were derived from cross-sectional observations and based merely on the statistical distribution of values. Therefore, we conducted a prospective cohort study to identify 24-hour ABP relation prognosis. We obtained measurements 1542 subjects (565 men) aged 40 years over general rural Japanese community then followed-up their survival status. There 117 deaths during follow-up period (mean, 6.2 years). The association between baseline mortality, examined by Cox proportional hazards regression model adjusted possible confounding factors, showed better fit with second-degree equation than first-degree equation. On basis results this analysis, identified following as optimal ranges that predict best prognosis: 120 133 mm Hg systolic 65 78 diastolic pressure. 24-Hour >134/79 <119/64 related increased risks cardiovascular noncardiovascular respectively. This is first report propose prognostic criterion.