The Metabolic Syndrome Is a Stronger Risk Factor for Early Carotid Atherosclerosis in Women Than in Men

• DOI: 10.1161/01.str.0000166196.31227.91
• Publication Date: 2005-05-13T00:34:58Z
• Authors: Bernhard Iglseder; Paula Cip; Liane Malaimare; Gunther Ladurner; Bernhard Paulweber
• Keywords: Stroke

The metabolic syndrome (MetS) is associated with an increased risk for subsequent development of type 2 diabetes mellitus, cardiovascular disease, and stroke. Type increases the stroke coronary heart disease in women to a greater extent than men, thus question arises whether there are sex differences association early atherosclerosis MetS.1588 middle-aged Austrian subjects (1001 males, 587 females) were included present study. MetS was defined by criteria National Cholesterol Education Program Adult Treatment Panel III. Early assessed intima-media thickness (IMT) plaques (B-score) carotid arteries.B-score artery IMT parameters significantly higher MetS. After adjustment established factors, difference B-score remained significant only women. Computed common values using general linear model equations age, body mass index, low-density lipoprotein cholesterol as covariates displayed highest men (811.8+/-9.5 microm). Women (797.6+/-15 microm) without (788.8+/-5 showed similar IMTs, whereas presented lower (735.6+/-7 Among subcomponents MetS, high-density strongest impact on blood glucose ranked first women.The effect more pronounced females. components differs between