Do Silent Brain Infarctions Predict the Development of Dementia After First Ischemic Stroke?

• DOI: 10.1161/01.str.27.5.904
• Publication Date: 2011-06-17T20:08:03Z
• Authors: N. M. Bornstein; A. Y. Gur; T. A. Treves; I. Reider-Groswasser; B. D. Aronovich; S. S. Klimovitzky; D. Varssano; A. D. Korczyn
• Keywords: Stroke; Brain infarction; Brain ischemia

Background and Purpose Silent brain infarctions (SBI) are common findings in advanced age, but their relationship to dementia is still uncertain. The present study was designed evaluate whether SBI predict the development of after first clinical ischemic stroke. Methods We blindly studied admission CT scans 175 consecutive nondemented patients presenting with stroke that clinically episode. were defined as evidence infarcts not compatible acute event. subsequently followed for mental state 5 years. Survival analysis, wherein onset end point, performed on total sample population conducted separately those without at admission. Results Dementia developed 56 (32%), including 22 63 (35%) 34 112 (30%) SBI. Thus, related Conclusions Our data indicate do